A Synthesis of Vitamin B6
نویسندگان
چکیده
منابع مشابه
Heme synthesis in vitamin B6 and pantothenic acid deficiencies.
Shemin and coworkers (14) showed that the a-carbon and nitrogen atoms of glycine were precursors of specific atoms of the heme molecule. This was substantiated by Muir and Neuberger (5, 6). Other carbon atoms were shown to come from acetate (5-7) or succinate (8). The nature of the intermediate precursors synthesized from these metabolites remained unknown until the structure for urinary porpho...
متن کاملHepatic Vitamin B6 Metabolism
nM. Thus, pyridloxal-P is the principal B6 vitaimer in plasma. Durinig pyridoxine stupplemiienitation, mealn plasnma levels of the B6 vitaimers anid pyridoxic acidl increasedl to 655±122 aindl 222±55 nM, respectively. The plasma content of pyridoxal-P aind( pyricloxic acidl increased 6-7-fold anid thatt of pyridoxal, 12-fold, but the pyridloxiine level did niot increase. Isolatedlhepatocytes, 1...
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In 1949, Rinehart and Greenberg reported that marked arteriosclerosis occurs in vitamin-B6-deficient monkeys. The present study investigates the relationship between vitamin B6 and arteriosclerosis and summarizes the results. I found that thrombogenesis, disorder of collagen metabolism and production of free radicals may be the processes that cause arteriosclerosis in human and experimental ani...
متن کاملPlasma vitamin B6 vitamers before and after oral vitamin B6 treatment: a randomized placebo-controlled study.
BACKGROUND Vitamin B(6) has attracted renewed interest because of its role in homocysteine metabolism and its possible relation to cardiovascular risk. We examined the plasma B(6) vitamers, pyridoxal 5'-phosphate (PLP), pyridoxal (PL), pyridoxine (PN), and 4-pyridoxic acid (4-PA) before and after vitamin B(6) supplementation. METHODS Patients (n = 90; age range, 38-80 years) undergoing corona...
متن کاملVitamin B6: a molecule for human health?
Vitamin B6 is an intriguing molecule that is involved in a wide range of metabolic, physiological and developmental processes. Based on its water solubility and high reactivity when phosphorylated, it is a suitable co-factor for many biochemical processes. Furthermore the vitamin is a potent antioxidant, rivaling carotenoids or tocopherols in its ability to quench reactive oxygen species. It is...
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ژورنال
عنوان ژورنال: Agricultural and Biological Chemistry
سال: 1961
ISSN: 1881-1280,0002-1369
DOI: 10.1271/bbb1961.25.240